GC Image LCxLC Edition Users' Guide

New Features and Improvements in Release 2.2

GC Image LCxLC Edition Release 2.2 (June 2011) has many new features and improvements. See the GC Image LCxLC Edition Users' Guide for full documentation. GC Image LCxLC Edition Release 2.2 requires Windows XP Service Pack 2 or later operating system.

Cross-Sample Analysis with the Image Investigator™

GC Image LCxLC Edition R2.2 introduces a new framework for automated non-targeted cross-sample analysis with the Image Investigator™. The framework supports automated comprehensive feature generation, alignment, and matching across many samples. The framework uses advanced peak-region features which provide a high degree of selectivity and implicit cross-sample feature matching. The Image Investigator allows users to:

Specify a customized feature template for targeted analysis or generate a comprehensive peak-region template for non-targeted analysis.
Report mean, standard deviation, and relative standard deviation for individual features.
Filter features based on various statistics and generate a refined feature template.
Assign samples to classes and compute Fisher ratios for individual features.
Export feature tables for external analysis.

1D View with Synchronized Viewing and Navigation

GC Image LCxLC Edition R2.2 introduces a 1D View tool that displays one-dimensional slices of a chromatogram that are fully synchronized and interactive with the Image Viewer.

1D View displays multiple adjacent 1D slices from open image views of TIC, SIC or CLIC data along either the Column I or Column II dimension.
1D View allows users to add additional 1D slices for specific spectral ranges.
1D View provides many controls including grouping, value mapping, zooming, and precision navigation.
1D View allows users to save current projections as graphs for presentation or as raw data values for external analysis.

A new control setting allows users to synchronize zooming and navigating on all open Image Viewers.

New 3D Visualization for Multi-Spectral Data

GC Image LCxLC Edition R2.2 introduces two new 3D visualization features for LCxLC-MS data.

Spectral colorization for 3D View maps various user-specified spectral components to different group colors, revealing spectral information embedded within large and complex LCxLC-MS data.
MS Cube supports exploring LCxLC-MS data in a 3D space whose dimensions are Column I, Column II, and MS. LCxLC-MS data is displayed as a cloud of points in the 3D space. The view allows the user to quickly browse any orthogonal slice (Col IxCol II, Col IxMS, Col IIxMS) and the spectrum at any point to discover interesting patterns.

New and Improved I/O Support

GC Image LCxLC Edition R2.2 has new and improved I/O facilities.

The software supports importing Agilent Mass Hunter ".D" folders directly with the MassHunter Data Access Component (MHDAC) 2.0.
The software supports transposing an image during the Import Image process.
Users can specify Start Acquisition Time in the Import Dialog to import data at a specific acquisition time.
Users can choose whether to export the display dimensions of an open chromatogram in the export settings.

The people of GC Image welcome your suggestions of new features, your comments about existing features and documentation, and reports of any problems. We strive to make GC Image software meet the needs of our users in their many varied applications.

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