GC Image LCxLC-HRMS Edition Users' Guide

New Features and Improvements in Version 2.7

GC Image LCxLC-HRMS Edition 2.7 has many new features and improvements. See the GC Image LCxLC-HRMS Edition Users' Guide for full documentation.

What's New in Version 2.7 Release 3 (February 2018)


Improved Support for Auto Processing Agilent 2D-LC Data

GC Image LCxLC-HRMS Edition 2.7 Release 3 includes the following improvements for processing Agilent 2D-LC data automatically:

Process 2D-LC Runs

Improved Support for AB SCIEX .Wiff Files

GC Image LCxLC-HRMS Edition 2.7 Release 3 includes the following improvements for importing AB SCIEX .Wiff data files:

In addition, the software includes the following improvements for Import and Merge:

New Improvements for Peak Detection, Identification, and Review

GC Image LCxLC-HRMS Edition 2.7 Release 3 has improved and new features for peak detection, compound identification, and review.

Import Compound List

The software includes new settings to control how a reference MS is extracted and used when adding a bob to the template:

Template - Auto Reference MS Configuration

In addition, the software includes new improvements to assist spectral review:

Spectral Review with Reference MS and Hit List

New Improvements for Multi-Sample Analysis with Investigator

GC Image LCxLC-HRMS Edition 2.7 Release 3 includes the following improvements on Investigator for multi-sample analysis:

In addition, the software has a new CLIC function MSString() that allows users to export blob spectra as part of Blob Table to Investigator or external programs.

What's New in Version 2.7 Release 2 (October 2017)


Improved Support for Heart-Cutting, Variable Modulation, and 2D-LC

GC Image LCxLC-HRMS Edition 2.7 Release 2 has improved support for small chromatograms, such as ones acquired with heart-cutting including:

For chromatograms acquired with variable modulation, the software has the following improvements:

In addition, the software has a new option to combine comprehensive cuts into a single modulation region when Import Agilent 2D-LC data.

Improved Support for Retention Index Calibration

GC Image LCxLC-HRMS Edition 2.7 Release 2 includes improvements to support generic retention index calibration.

RI Table Configuration

New Improvements for Mass Spectral Viewing and Calibration

GC Image LCxLC-HRMS Edition 2.7 Release 2 has new improvements for streamlining the work flow for mass calibration including:

In addition, the software has new improvements for the default MS mode including:

New Library Search Features

GC Image LCxLC-HRMS Edition 2.7 Release 2 includes significant improvements for Library Search features.

Library Search Settings

What's New in Version 2.7 Release 1 (June 2017)


Improved Agilent 2D-LC Data Support

GC Image LCxLC-HRMS Edition 2.7 Release 1 now can utilize the Agilent 2D-LC specific metadata to import multiple heart-cutting, high-resolution sampling (i.e. selective), or comprehensive 2D-LC data, and construct a 2D chromatogram automatically.

Import Agilent 2D-LC

Large Data File Support

GC Image LCxLC-HRMS Edition 2.7 Release 1 includes significant improvements for reading and writing large CDF files, which are used as the file store for MS data.

CDF Read Time Graph

Mass Spectra Centroiding, Calibration, and Viewing

GC Image LCxLC-HRMS Edition 2.7 Release 1 has new and improved operations for mass calibration with HRMS data, including:

Q-Ion properties

MS Library Search for Area Objects

GC Image LCxLC-HRMS Edition 2.7 Release 1 introduces MS library search supports for areas.

New Hit List for Area Object

New Quantifier Ion Properties

GC Image LCxLC-HRMS Edition 2.7 Release 1 has new properties and improved operations for quantifier ions, including:

Q-Ion properties

New Calibration and Quantification Tools

GC Image LCxLC-HRMS Edition 2.7 Release 1 introduces new tools for calibration and quantification. The process for generating calibration tables is simplified by a new UI and options, including:

New Calibration Table