GC Image LCxLC Edition Users' Guide

New Features and Improvements in Release 2.5

GC Image LCxLC Edition Release 2.5 (September 2014) has many new features and improvements. See the GC Image LCxLC Edition Users' Guide for full documentation. GC Image LCxLC Edition R2.5 requires Microsoft Windows Vista or later operating system. GC Image LCxLC Edition R2.5 (64-bit) requires a 64-bit Windows operating system. For Agilent MassHunter or JEOL AccuTOF users, the software requires Microsoft .Net Framework 4.0 or later.

QA Rapid Screen

GC Image LCxLC Edition R2.5 introduces QA Rapid Screen, which allows rapid inspection of analytical results. Users select peaks or regions for review, either interactively or with a CLIC expression, and then QA Rapid Review presents a set of user-configurable views for each. For example, a user might configure a perspective with views of a zoomed image, 1D slices, the MS view, and a SIC. Then, as each peak or region is reviewed, all selected views of the object are shown, presenting a tightly integrated perspective on each analysis. Features include:

New and Improved Operations and Support for HRMS

GC Image LCxLC Edition R2.5 has new and improved features for HRMS data, including:

New Tools for Blob Detection

GC Image LCxLC Edition R2.5 has a new Interactive Blob Detection tool that allows users to specify and interactively experiment with blob detection configuration settings and filters.  In addition, the Blob Detection configuration now allows users to constrain blob detection with a user-defined CLIC Blob Detection Filter, i.e., a CLIC expression that constrains blob detection.  These two new tools work well together: the Interactive Blob Detection tool can be used to build and save a CLIC Blob Detection Filter.

New Tools for NIST14 Retention Indices and MS/MS Library Search

The new 2014 edition of the popular NIST/EPA/NIH Mass Spectral Library and Search Software (NIST14) integrates retention indexes into its searches and hitlists and significantly expands its EI and MS/MS libraries.  GC Image LCxLC Edition R2.5 has new features to support these new capabilities, including

New and Improved Operations for Data Processing

GC Image LCxLC Edition R2.5 has new and improved operations for data processing, including:

Enhanced User Interfaces for Template Transformations

New and Improved Operations in Image Investigator™

In GC Image LCxLC Edition R2.5, Image Investigator supports:

New Support for 3D Modeling and Visualizations including 3D Fly-by Videos

GC Image LCxLC Edition R2.5 can export its 3D View to a VTK file, an open-source file format for 3D Graphics. Then, that file, which represents the 2D chromatogram with elevation, can be accessed and manipulated in many other programs, including the free, open-source, multiplatform data analysis and visualization software ParaView, which can be used to generate 3D fly-by videos.

Molecular Weight Distribution Averages

GC Image LCxLC Edition R2.5 supports a preliminary set of molecular weight distribution averages, e.g., for polymer analysis. Additional features will be added in future releases. The blob and area tables can be configured to report the following averages based on linear calibration of calibrants characterized by peak molecular weight (Mp).

Other New and Improved Operations

GC Image LCxLC Edition R2.5 has many other new and improved operations, including: