GC Image LCxLC-HRMS Edition Users' Guide
New Features and Improvements in Version 2.9
GC Image LCxLC-HRMS Edition 2.9 has many new features and improvements. See
the GC Image LCxLC-HRMS Edition Users' Guide for full
What's New in Version 2.9 Release 1 (July 2019)
Version 2.9R1 has a new default filter type, Median-Mean, for
the Default Baseline Correction
algorithm and automated noise estimation. This new filter can handle a
rapid changing baseline along Column I dimension better than the
filter in older versions.
Version 2.9R1 has a new feature,
Signal Noise, that allows users to recalculate noise after
baseline correction. It supports estimating noises from
individual strides and/or specified regions, and allows users to
specify background regions manually if automated noise estimation was
affected by some background artifacts. Also, the new operation
provides three different ways to estimate noise, IID, Standard
Deviation, and Peak-to-Peak, and can be added to a method for batch
- Blob Table now can be
configured to show Peak-to-Peak noise and SNR columns.
- Tools > Visualize Data now computes and displays both
population and sample standard deviations of data point values in the
Version 2.9R1 has a new Detect Blob cursor mode for Local Blob Detection. The mode supports
detecting a blob at the location indicated by the mouse double click
or drag selection. If the location is not contained by existing blobs,
the program will detect a blob at the location automatically. If the
location is contained by some existing blob, the program will select
the blob, and invoke Local Blob Detection to allow users to re-detect
blobs within the blob area.
- Local Blob Detection now
remembers the recently used settings.
- Blob Table now can be configured to show the
following new pixel-based peak width properties:
, in addition to axis-unit-based properties, which can be used
to filter noisy artifacts detected as blobs.
- Size I (pixel) and Size II (pixel): Size of column I and
column II bounding box in pixels.
- Size I(50.0) (pixel) and Size II(50) (pixel): Size of
column I and column II bounding box for values 50% of peak in
- Size I(w) (pixel) and Size II(w) (pixel): Size of column I
and column II bounding box for values w% of peak in pixels.
- Interactive Blob Detection now
presents a list of suggested properties including Retention I,
Retention II, Size II (pixel), Area (pixel),
Peak Value, Volume, and SNR, when adding a new
constraint as a filter. Also, all blob properties are organized into
GC Image LCxLC-HRMS Edition 2.9R1 has new improvements for Template > Import Compound
- A new option for including all unspecified columns as custom
attributes. When this option is selected, all unspecified columns will
be imported into the Description field of corresponding template peaks
as custom attributes.
- A new import setting, Apply Phase shift that allows applying a shift
to the imported compound peaks. The user can choose to apply the same
phase shift as the image or specify a shift amount. The imported
compound peaks will wrap around the image if required.
- Compounds that are out of the lower retention bounds of the
chromatogram are now highlighted in red. An error message will
be shown if no valid compounds can be imported.
Version 2.9R1 has new improvements for Investigator,
- Investigator now supports filtering entries in Images and
Compounds perspectives, in addition to Summary perspective. In Images Perspective,
images can be filtered by name or class label. Blob Table, Area Table,
and Blob Set Table of an image can be filtered by the selected
column. In Compounds
Perspective, compounds can be filtered by name.
- In Attributes
Perspective, Investigator now runs Principal Component Analysis
(PCA) in the background, which allows users to switch between tabs
and continue working while it is being processed. Only one PCA can be
processed at a time. The process can be canceled using the Cancel PCA
button at any time.
- Investigator now has targeted views in Compounds
- Trend: Line charts show trends of the selected
attributes based on the sorting order of the current table.
- Distribution: Bar charts show how values of the
selected attributes are distributed across sample images.
- Spectra: Spectral views show the spectra of the
selected compound across sample images if Spectrum
attribute is available.
Version 2.9R1 has other new and improved operations, including:
- Edit > CLIC Expression now lists all blob
properties in easy-to-find categories next to the Functions
- Configure > RI table now presents a list
of suggested compound properties including Library BP, Library
Molecular Weight, and Library RI, when populating the table.
In addition, the Populate UI organizes all blob properties into
- All figures and chromatogram images in Reports
are now saved as PNG instead of JPEG to provide the best quality for
presentation. In addition, File > Export Image as
Picture now can save a chromatogram image in a GIF format.
GC Image™ LCxLC-HRMS Edition Users' Guide ©
2001–2019 by GC Image, LLC, and the University of Nebraska.